 Vol.45 n° 3
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Progressive Premalignant and Malignant Development (Metachronous Appearance) in Multiple Burn Scars (Marjolin's Ulcers) Report of a Rare Case and Review of the Literature Desenvolvimento Pré-Maligno e Maligno Progressivo (Metácrono) em Múltiplas Cicatrizes de Queimadura (Úlceras de Marjolin)- Relato de Caso e Revisão da Bibliografia Horácio M. Scigliano; Romeu Ferreira Daroda; Marco Antônio da Silva Pereira; Marisa I. Suarez e Marcia Ferreira Daroda
Abstract
The eponym Marjolin's ulcer is used to describe the malignant transformation of any skin ulcer or scar. A 35-year-old white woman sustained a thermal burn injury over her lower half of the body when she was 8 years old. After 16 years of the event and over 9 years, metachronous skin ulcers, pseudocarcinomatous hyperplasia and well differentiated squamous cell carcinomas occured, mainly on both lower limbs. The clinical history, histologic aspects, histogenesis, follow-up data and therapeutic considerations are discussed along with a review of the relevant literature.
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Revista Brasileira de Cancerologia - Volume 45 n°3 Jul/Ago/Set 1999